Medical Research, UWA Centre for

Books and Chapters

Laing, N.G. The Sarcomere and Skeletal Muscle Disease, U.S.A., Springer-Verlag Berlin (2008)

North, K.N. and Laing, N.G. Skeletal Muscle Alpha-Actin Diseases, The Sarcomere and Skeletal Muscle Disease, ed Nigel G. Laing, U.S.A., Springer-Verlag Berlin, 642: pp 15-27 (2008)

Nowak, K.J. Therapeutic Approaches for the Sarcomeric Protein Diseases, The Sarcomere and Skeletal Muscle Disease, ed Nigel G. Laing, U.S.A., Springer-Verlag Berlin, 642: pp 207-223 (2008)

Journal Articles

Almeida, O.P., Schwab, S.G., Lautenschlager, N.T., Morar, B., Greenop, K.R., Flicker, L. and Wildenauer, D.B. KIBRA genetic polymorphism influences episodic memory in later life, but does not increase the risk of mild cognitive impairment, Journal of Cellular and Molecular Medicine, 12: pp 1672-1676 (2008)

Ambrosini, G.L., Fritschi, L., de Klerk, N., Mackerras, D. and Leavy, J.E. Dietary Patterns Identified Using Factor Analysis and Prostate Cancer Risk: A Case Control Study in Western Australia, Annals of Epidemiology, 18: pp 364-370 (2008)

Ambrosini, G.L., de Klerk, N.H., Mackerras, D., Leavy, J.E. and Fritschi, L. Dietary patterns and surgically treated benign prostatic hyperplasia: a case control study in Western Australia, BJU International, 101: pp 853-860 (2008)

Ambrosini, G.L., de Klerk, N.H., Fritschi, L., Mackerras, D. and Musk, A.W. Fruit, vegetable, vitamin A intakes, and prostate cancer risk, Prostate Cancer and Prostatic Diseases, 11: pp 61-66 (2008)

Aston-Mourney, K., Proietto, J., Morahan, G. and Andrikopoulos, S. Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin, Diabetolgia, 51: pp 540-545 (2008)

Baade, P., Carriere, P. and Fritschi, L. Trends in testicular germ cell cancer incidence in Australia, Cancer Causes Control, 19: pp 1043-1049 (2008)

Benke, G., Sim, M.R., McKenzie, D.P., MacFarlane, E., Del Monaco, A., Hoving, J.L. and Fritschi, L. Comparison of First, Last and Longest Held Jobs as Surrogates for All Jobs in Estimating Cumulative Exposure in Cross-Sectional Studies of Work-Related Asthma, Annals of Epidemiology, 18: pp 23-27 (2008)

Chakera, A., Seeber, R.M., John, A.E., Eidne, K.A. and Greaves, D.R. The Duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization, Molecular Pharmacology, 73: pp 1362-1370 (2008)

Clarke, N.F., Kolski, H., Dye, D.E., Lim, E., Smith, R.L.L., Patel, R., Fahey, M.C., Bellance, R., Romero, N.B., Johnson, E.S., Labarre-Vila, A., Monnier, N., Laing, N.G. and North, K.N. Mutations in TPM3 are a common cause of congenital fiber type disproportion, Annals of Neurology, 63:3, pp 329-337 (2008)

Cohen, R.J., Shannon, B.A., Phillips, M., Moorin, R., Wheeler, T.M. and Garrett, K.L. Central Zone Carcinoma of the Prostate Gland: A Distinct Tumor Type With Poor Prognostic Features, The Journal of Urology, 179: pp 1762-1767 (2008)

Concannon, P., Onengut-Gumuscu, S., Todd, J.A., Smyth, D.J., Pociot, F., Bergholdt, R., Akolkar, B., Erlich, H.A., Hilner, J.E., Julier, C., Morahan, G., Nerup, J., Nierras, C.R., Chen, W. and Rich, S.S. A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3, Diabetes, 57: pp 2858-2861 (2008)

Dalrymple, M.B., Pfleger, K. and Eidne, K.A. G protein-coupled receptor dimers: Functional consequences, disease states and drug targets, Pharmacology & Therapeutics, 118: pp 359-698 (2008)

Depreter, M.G.L., Blair, N.F., Gaskell, T.L., Nowell, C.S., Davern, K., Pagliocca, A., Stenhouse, F.H., Farley, A.M., Fraser, A., Vrana, J., Robertson, K., Morahan, G., Tomlinson, S.R. and Blackburn, C.C. Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells, Proceedings of the National Academy of Sciences of the United States of America, 105: pp 962-966 (2008)

Dromey, J.R. and Pfleger, K. G Protein Coupled Receptors as Drug Targets: The Role of scientific symbols -β Arrestins, Endocrine, Metabolic & Immune Disorders - Drug Targets, 7: pp 51-61 (2008)

Du, R., Lu, K.V., Petritsch, C., Liu, P., Ganss, R., Passegué, E., Song, H., VendenBurg, S., Johnson, R.S., Werb, Z. and Bergers, G. HIF1 Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion, Cancer Cell, 13: pp 206-220 (2008)

Du, R., Petritsch, C., Lu, K., Liu, P., Haller, A., Ganss, R., Song, H., VandenBurg, S. and Bergers, G. Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM, Neuro-Oncology, 10: pp 254-264 (2008)

Endersby, R., Majewski, I.J., Winteringham, L., Beaumont, J.G., Samuels, A., Scaife, R., Lim, E., Crossley, M., Klinken, S.P. and Lalonde, J.P. Hls5 regulated erythroid differentiation by modulating GATA-1 activity, Blood, 111: pp 1946-1950 (2008)

Fourlanos, S., Varney, M.D., Tait, B.D., Morahan, G., Honeyman, M.C., Coleman, P.G. and Harrison, L.C. The Rising Incidence of Type 1 Diabetes Is Accounted for by Cases With Lower-Risk Human Leukocyte Antigen Genotypes, Diabetes Care, 31: pp 1546-1549 (2008)

Fritschi, L., Shirangi, A., Robertson, I.D. and Day, L.M. Trends in exposure of veterinarians to physical and chemical hazards and use of protection practices, International Archives of Occupational and Environmental Health, 81: pp 371-378 (2008)

Fritschi, L., Hoving, J.L., Sim, M.R., del Monaco, A., MacFarlane, E., McKenzie, D., Benke, G. and de Klerk, N. All cause mortality and incidence of cancer in workers in bauxite mines and alumina refineries, International Journal of Cancer, 123: pp 882-887 (2008)

Ha, J., Phillips, M. and Sieunarine, K. A Retrospective Review of the Outcomes of Vacuum-assisted Closure Therapy in a Vascular Surgery Unit, Wounds, 20: pp 221-229 (2008)

Hamzah, J., Nelson, D., Moldenhauer, D., Arnold, G., Hämmerling, G.J. and Ganss, R. Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumours enhances immunotherapy in mice, Journal of Clinical Investigation, 118: pp 1691-1699 (2008)

Hamzah, J., Jugold, M., Kiessling, F., Rigby, P.J., Manzur, M., Marti, H.H., Rabie, T., Kaden, S., Gröne, H-J., Hämmerling, G.J., Bernd, A. and Ganss, R. Vascular normalization in Rgs5-deficient tumours promotes immune destruction, Nature, 453: pp 410-415 (2008)

Harrison, L.C., Honeyman, M.C., Morahan, G., Wentworth, J.M., Elkassaby, S., Colman, P.G. and Fourlanos, S. Type 1 diabetes: Lessons for other autoimmune diseases?, Journal of Autoimmunity, 31: pp 306-310 (2008)

Ilkovski, B., Mokbel, N., Lewis, R.A., Walker, K., Nowak, K.J., Domazetovska, A., Laing, N.G., Fowler, V.M., North, K.N. and Cooper, S.T. Disease Severity and Thin Filament Regulation in M9R TPM3 Nemaline Myopathy, Journal of Neuropathology and Experimental Neurology, 67: pp 867-877 (2008)

Irmansyah, Schwab, S.G., Heriani, Handoko, H.Y., Kusumawardhani, A., Widyawati, I., Amir, N., Nasrun, M.W.S., Holmans, P., Knapp, M. and Wildenauer, D.B. Genome-Wide Scan in 124 Indonesian Sib-Pair Families With Schizophrenia Reveals Genome-Wide Significant Linkage to a Locus on Chromosome 3P26-21, American Journal of Medical Genetics Part B Neuropsychiatrics Genetics, 147B: pp 1245-1252 (2008)

Jellicoe, M.M., Nichols, S.J., Callus, B.A., Baker, M.V., Barnard, P.J., Berners-Price, S.J., Whelan, J.M., Yeoh, G.C. and Filipovska, A. Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound, Carcinogenesis, 29: pp 1124-1133 (2008)

Kocan, M., See, B.H., Seeber, R.M., Eidne, K.A. and Pfleger, K.D.G. Demonstration of Improvements to the Bioluminescence Resonance Energy Transfer (BRET) Technology for the Monitoring of G Protein-Coupled Receptors in Live Cells, Journal of Biomolecular Screening, 13: pp 888-898 (2008)

Kolsch, H., Jessen, F., Wiltfang, J., Lewczuk, P., Dichgans, M., Kornhuber, J., Frolich, L., Heuser, I., Peters, O., Schulz, J.B., Schwab, S.G. and Maier, W. Influence of SORL1 gene variants: Association with CSF amyloid-B products in probable Alzheimer's disease, Neuroscience Letters, 440: pp 68-71 (2008)

Laing, N.G. Multiplicity of experimental approaches to therapy for genetic muscle diseases and necessity for population, Journal of Muscle Research and Cell Motility, 29: pp 247-252 (2008)

Lehtokari, V-L., Pelin, K., Donner, K., Voit, T., Rudnick-Schoneborn, S., Stoetter, M., Talim, B., Topaloglu, H., Laing, N.G. and Wallgren-Pettersson, C. Identification of a founder mutation in TPM3 in nemaline myopathy patients of Turkish origin, European Journal of Human Genetics, 16: pp 1055-1061 (2008)

Lindsey-Temple, S.E., Pham, T.K., Glendenning, P., Phillips, M. and Waterer, G.W. Endotoxin induced TNF and IL-10 mRNA production is higher in male than female donors: Correlation with elevated expression of TLR4, Cellular Immunology, 251: pp 69-71 (2008)

Ludewick, H.P., Schwab, S.G., Albus, M., Lerer, B., Maier, W., Trixler, M. and Wildenauer, D.B. No support for an association with TAAR6 and schizophrenia in a linked population of European ancestry, Psychiatric Genetics, 18: pp 208-210 (2008)

Lynch, B.M., Youlden, D., Fritschi, L., Newman, B., Pakenham, K.I., Leggett, B., Owen, N. and Aitken, J.F. Self-reported information on the diagnosis of colorectal cancer was reliable but not necessarily valid, Journal of Clinical Epidemiology, 61: pp 498-504 (2008)

Mancebo, E., Moreno-Pelayo, M.A., Mencia, A., de la Calle-Martin, O., Allende, L.M., Sivadorai, P., Kalaydjieva, L., Bertranpetit, J., Coto, E., Antolin, S.C., Ruiz-Contreras, J. and Paz-Artal, E. Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies, MOLECULAR IMMUNOLOGY, 45: pp 479-484 (2008)

Manzur, M., Hamzah, J. and Ganss, R. Modulation of the "blood-tumor" barrier improves immunotherapy, Cell Cycle, 7: pp 2452-2455 (2008)

McCaul, K.A., Fritschi, L., Baade, P. and Coory, M. The incidence of second primary invasive melanoma in Queensland, 1982-2003, Cancer Causes Control, 19: pp 451-458 (2008)

Meuleners, L.B., Hendrie, D., Lee, A.H. and Legge, M. Effectiveness of the Black Spot Programs in Western Australia, ACCIDENT ANALYSIS AND PREVENTION, 40:3, pp 1211-1216 (2008)

Mihaylova, V., Hantke, J., Cherninkova, S., Krastev, S., Radionova, M., Raicheva, M., Sinigerska, I., Jelev, H., Jablensky, A., Kalaydjieva, L. and Tournev, I. Severe neuropsychiatric symptoms in two siblings with intermediate type of Niemann-Pick disease, JOURNAL OF NEUROLOGY, 255: pp 1434-1435 (2008)

Mina, K., Fritschi, L., Johnson, K.C. and The Canadian Cancer Registries An Inverse association Between Preserved Fish and Prostate Cancer: Results From a Population-Based Case-Control Study in Canada, Nutrition and Cancer- An International Journal, 60: pp 222-226 (2008)

Morahan, G., Balmer, L.A. and Monley, D. Establishment of "The Gene Mile": a resource for rapid identification of complex trait genes, Mammalian Genome, 19: pp 390-393 (2008)

Morahan, G., Peeva, V., Mehta, M. and Williams, R. Systems genetics can provide new insights in to immune regulation and autoimmunity, Journal of Autoimmunity, 31: pp 233-236 (2008)

Muller-Berghaus, J., Kemper, M.J., Hoppe, B., Querfeld, U., Müller-Wiefel, D.E., Morahan, G., Schadenorf, D. and Tenbrock, K. The clinical Course of steroid-sensitive childhood nephrotic syndrome is associated with a functional IL12B Promoter polymorphism, Nephrology Dialysis Translantation, 23: pp 3841-3844 (2008)

Musk, A.W., de Klerk, N.H., Reid, A., Ambrosini, G.L., Fritschi, J.E., Olsen, N.J., Merler, E., Hobbs, M.S. and Berry, G. Mortality of former crocidolite (blue asbestos) miners and millers at Wittenoom, Occupational and Environmental Medicine, 65: pp 541-543 (2008)

Peeva, V.K., Lynch, J.L., Desilva, C.J.S. and Swanson, N.R. Evaluation of automated and conventional microarray hybridization: a question of data quality and best practice?, BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 50: pp 181-190 (2008)

Pfleger, K., Pawson, A.J. and Millar, R.P. Changes to Gonadotropin-Releasing Hormone (GnRH) Receptor Extracellular Loops Differtially Affect GnRH Analog Binding and Activation: Evidence for Distinct Ligand-Stabilized Receptor Conformations, Endocrinology, 149: pp 3118-3129 (2008)

Quednow, B.B., Kühn, K.U., Mössner, R., Schwab, S.G., Schuhmacher, A., Maier, W. and Wagner, M. Sensorimotor gating of schizophrenia patients is influenced by 5-HT2A receptor polymorphisms, Biological Psychiatry, 64: pp 434-437 (2008)

Ravenscroft, G., Colley, S.M., Walker, K.R., Clement, S., Bringans, S., Lipscombe, R., Fabian, V.A., Laing, N.G. and Nowak, K.J. Expression of cardiac x-actins spares extracular muscles in skeletal muscle x-actins diseases - Quantification of striated x-actins by MRM-mass spectrometry, Neuromuscular Disorders, 18: pp 953-958 (2008)

Saggers-Gray, L., Heriani, H., Handoko, H.Y., Irmansyah, I., Kusumawardhani, A.A.A.A., Widyawati, I., Amir, N., Nasrun, M.W.S., Schwab, S.G. and Wildenauer, D.B. Association of PIP5K2A With Schizophrenia: A Study in an Indonesian Family Sample, American Journal of Medical Genetics Part B Neuropsychiatris Genetics, 147B: pp 1310-1313 (2008)

Schwab, S.G., Plummer, C.M., Albus, M., Borrmann-Hassenbach, M., Lerer, B., Trixler, M., Maier, W. and Wildenauer, D.B. DNA sequence variants in the metabotropic glutamate receptor 3 and risk to schizophrenia: an association study, Psychiatric Genetics, 18: pp 25-30 (2008)

Schwab, S.G. and Wildenauer, D.B. Research on causes for schizophrenia: Are we close?, Schizophrenia Research, 102: pp 29-30 (2008)

Shirangi, A., Fritschi, L. and Holman, C.D.J. Maternal occupational exposures and risk of spontaneous abortion in veterinary practice, Occupational and Environmental Medicine, 65: pp 719-725 (2008)

Sims, A.M., Shephard, N., Carter, K.W., Doan, T., Dowling, A., Duncan, E.L., Eisman, J., Jones, G., Nicholson, G., Prince, R.L., Seeman, E., Thomas, G., Wass, J.A. and Brown, M.D. Genetic Analyses in a Sample of Individuals With High or Low BMD Demonstrates Association With Multiple Wnt Pathway Genes, Journal of Bone and Mineral Research, 23: pp 499-506 (2008)

Sivadorai, P., Cherninkova, S., Bouwer, S., Kamenarova, K., Angelicheva, D., Seeman, P., Hollingsworth, K., Mihaylova, V., Oscar, A., Dimitrova, G., Kaneva, R., Tournev, I. and Kalaydjieva, L. Genetic heterogeneity and minor CYP1B1 involvement in the molecular basis of primary congenital glaucoma in Gypsies, CLINICAL GENETICS, 74:1, pp 82-87 (2008)

Thompson, B., Baade, P., Coory, M., Carrière, P. and Fritschi, L. Patterns of Surgical Treatment for Woman Diagnosed with early Breast cancer in Queensland, Annals of Surgical Oncology, 15: pp 443-451 (2008)

Tsaousidou, M.K., Ouahchi, K., Warner, T.T., Yang, Y., Simpson, M.A., Laing, N.G., Wilkinson, P.A., Madrid, R.E., Patel, H., Hentati, F., Patton, M.A., Hentati, A., Lamont, P.J., Siddique, T. and Crosby, A.H. Sequence Alterations within CYP7B1 Implicate Defective Cholestorol Homeostasis in Motor-Neuron Degeneration, American Journal of Human Genetics, 82:2, pp 510-515 (2008)

Vince, J.E., Chau, D., Callus, B., Wong, W., Hawkins, C.J., Schneider, P., Mckinlay, M., Benetatos, C.A., Condon, S.M., Chunduru, S.K., Yeoh, G.C., Brink, R., Vaux, D.L. and Silke, J. TWEAK-FN14 signaling induces lysosomal degradation of a clAP1-TRAF2 complex to sensitize tumor cells to TNFα, Journal Cell Biology, 182: pp 171-184 (2008)

Wagner, M., Schuhmacher, A., Schwab, S.G., Zobel, A. and Maier, W. The His452Tyr variant of the gene encoding the 5-HT2A receptor is specifically associated with consolidation of episodic memory in humans, International Journal of Neuropsychopharmacology, 11: pp 1163-1167 (2008)

Young, D.J., Bebbington, A., Anderson, A., Ravine, D., Ellaway, C., Kulkarni, A., de Klerk, N., Kaufmann, W. and Leonard, H. The diagnosis of autism in a female: could it be Rett syndrome?, European Journal Pediatriacs, 167: pp 661-669 (2008)

Zobel, A., Jessen, F., von Widdern, O., Schuhmacher, A., A. Höfels, S., Metten, M., Rietschel, M., Scheef, L., Block, W., Becker, T., Schild, H.H., Maier, W. and Schwab, S.G. Unipolar Depression and Hippocampal Volume: Impact of DNA Sequence Variants of the Glucocorticoid Receptor Gene, American Journal of Medical Genetics Part B Neuropsychiatrics Genetics, 147B: pp 836-843 (2008)

Others

Dan, Y.Y. and Yeoh, G.C. (Review)Liver stem cells: A scientific and clinical perspective, Journal of Gastroenterology and Hepatology, 23: pp 687-698, Australia (2008)

Viebahn, C.S. and Yeoh, G.C. (Review)What fires prometheus? The link between inflammation and regeneration following chronic liver injury, Various, 40: pp 855-873, England (2008)