Medical Research, UWA Centre for

Journal Articles

Agrawal, P.B., Strickland, C.D., Midgett, C., Morales, A., Newburger, D.E., Poulos, M.A., Tomczak, K.K., Ryan, M.M., Iannaccone, S.T., Crawford, T.O., Laing, N.G. and Beggs, A.H. Heterogeneity of Nemaline Myopathy Cases with Skeletal Muscle α-Actin Gene Mutations, Annals of Neurology, 56: pp 86-96 (2004)

Almeida, O.P., Lautenschlager, N., Flicker, L., Leedman, P., Vasikaran, S., Gelavis, A. and Ludlow, J. Association between homocysteine, depression, and cognitive function in community-dwelling older women from Australia, Journal of the American Geriatrics Society, 52: pp 327-328 (2004)

Britto, J.M., Lukehurst, S., Weller, R., Fraser, C., Qiu, Y., Hertzog, P. and Busfield, S.J. Generation and characterization of neuregulin-2-deficient mice, Molecular and Cellular Biology, 24: pp 8221-6 (2004)

Carrello, A., Allan, R.K., Morgan, S.L., Owen, B.A.L., Mok, D., Ward, B.K., Minchin, R.F., Toft, D.O. and Ratajczak, T. Interaction of the Hsp90 cochaperone cyclophilin 40 with Hsc70, Cell Stress & Chaperones, 9: pp 167-181 (2004)

Celedón, J.C., Lange, C., Raby, B.A., Litonjua, A.A., Palmer, L.J., DeMeo, D.L., Reilly, J.J., Kwiatkowski, D.J., Chapman, H.A., Laird, N., Sylvia, J.S., Hernandez, M., Speizer, F.E., Weiss, S.T. and Silverman, E.K. The transforming growth factor-β1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD), Human Molecular Genetics, 13: pp 1649-1656 (2004)

Chaix, R., Austerlitz, F., Morar, B., Kalaydjieva, L. and Heyer, E. Vlax Roma history: what do coalescent-based methods tell us?, European Journal of Human Genetics, 12: pp 1-8 (2004)

Chan, D.C., Watts, G.F., Sussekov, A.V., Barrett, P.H.R., Yang, Z., Hua, J. and Song, S. Adipose tissue compartments and insulin resistance in overweight-obese Caucasian men, Diabetes Research and Clinical Practice, 63: pp 77-85 (2004)

Chan, D.C., Watts, G.F., Barrett, P.H.R., Whitfield, A.J. and van Bockxmeer, F.M. ATP-Binding Cassette Transporter G8 Gene As a Determinant of Apolipoprotein B-100 Kinetics in Overweight Men, Arteriosclerosis, Thrombosis, and Vascular Biology, 24: pp 2188-2191 (2004)

Chan, D.C., Barrett, P.H.R. and Watts, G.F. Lipoprotein transport in the metabolic syndrome: pathophysiological and interventional studies employing stable isotopy and modelling methods, Clinical Science, 107: pp 233-249 (2004)

Chua, A.C.G., Olynyk, J.K., Leedman, P.J. and Trinder, D. Non-transferrin bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary heochromatosis, Blood, 104: pp 1519-1525 (2004)

Churchill, G.A., Airey, D.C., Allayee, H., Angel, J.M., Attie, A.D., Beatty, J., Beavis, W.D., Belknap, J.K., Bennett, B., Berrettini, W., Bleich, A., Bogue, M., Broman, K.W., Buck, K.J., Buckler, E., Burmeister, M., Chesler, E.J., Cheverud, J.M., Clapcote, S., Cook, M.N., Cox, R.D., Crabbe, J.C., Crusio, W.E., Darvasi, A., Deschepper, C.F., Doerge, R.W., Farber, C.R., Forejt, J., Gaile, D., Garlow, S.J., Geiger, H., Gershenfeld, H., Gordon, T., Gu, J., Gu, W., de Haan, G., Hayes, N.L., Heller, C., Himmelbauer, H., Hitzemann, R., Hunter, K., Hsu, H.C., Iraqi, F.A., Ivandic, B., Jacob, H.J., Jansen, R.C., Jepsen, K.J., Johnson, D.K., Johnson, T.E., Kempermann, G., Kendziorski, C., Kotb, M., Kooy, R.F., Llamas, B., Lammert, F., Lassalle, J.M., Lowenstein, P.R., Lu, L., Lusis, A., Manly, K.F., Marcucio, R., Matthews, D., Medrano, J.F., Miller, D.R., Mittleman, G., Mock, B.A., Mogil, J.S., Montagutelli, X., Morahan, G., Morris, D.G., Mott, R., Nadeau, J.H., Nagase, H., Nowakowski, R.S., O'Hara, B.F., Osadchuk, A.V., Page, G.P., Paigen, B., Paigen, K., Palmer, A.A., Pan, H.J., Peltonen-Palotie, L., Peirce, J., Pomp, D., Pravenec, M., Prows, D.R., Qi, Z., Reeves, R.H., Roder, J., Rosen, G.D., Schadt, E.E., Schalkwyk, L.C., Seltzer, Z., Shimomura, K., Shou, S., Sillanpaa, M.J., Siracusa, L.D., Snoeck, H.W., Spearow, J.L., Svenson, K., Tarantino, L.M., Threadgill, D., Toth, L.A., Valdar, W., de Villena, F.P., Warden, C., Whatley, S., Williams, R.W., Wiltshire, T., Yi, N., Zhang, D., Zhang, M. and Zou, F. The Collaborative Cross, a community resource for the genetic analysis of complex traits, Nature Genetics, 36:11, pp 1133-1137 (2004)

Costa, C.F., Rommelaere, H., Waterschoot, D., Sethi, K.K., Nowak, K.J., Laing, N.G., Ampe, C. and Machesky, L.M. Myopathy mutations in α-skeletal-muscle actin cause a range of molecular defects, Journal of Cell Science, 117: p 33673377 (2004)

Dunlop, S.A., Tee, L.B.G., Stirling, R.V., Taylor, A.L., Runham, P.B., Barber, A.B., Kuchling, G., Rodger, J., Roberts, J.D., Harvey, A.R. and Beazley, L.D. Failure to restore vision after optic nerve regeneration in reptile: Interspecies variation in response to axotomy, The Journal of Comparative Neurology, 478: pp 292-305 (2004)

Goebel, H.H., Brockmann, K., Bönnemann, C.G., Warlo, I.A.P., Hanefeld, F., Labeit, S., Durling, H.J. and Laing, N.G. Actin-Related Myopathy Without Any Missense Mutation in the ACTA1 Gene, Journal of Child Neurology, 19: pp 149-153 (2004)

Gothert, J.R., Gustin, S.E., Anke, J., van Eekelen, J.A.M., Schmidt, U., Hall, M.A., Jane, S.M., Green, A.R., Gottgens, B., Izon, D.J. and Begley, C.G. Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium, Blood, 104: pp 1769-1777 (2004)

Ilkovski, B., Nowak, K.J., Domazetovska, A., Maxwell, A.L., Clement, S., Davies, K.E., Laing, N.G., North, K.N. and Cooper, S.T. Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms, Human Molecular Genetics, 13:16, pp 1727-1743 (2004)

Ingley, E., Tilbrook, P.A. and Klinken, S.P. New insights into the regulation of erythroid cells, IUBMB Life, 56:4, pp 177-184 (2004)

Jungbluth, H., Davis, M.R., Müller, C., Counsell, S., Allsop, J., Chattopadhyay, A., Messina, S., Mercuri, E., Laing, N.G., Sewry, C.A., Bydder, G. and Muntoni, F. Magnetic resonance imaging of muscle in congenital myopathies associated with RYR1 mutations, Neuromuscular Disorders, 14: pp 785-790 (2004)

Kaneva, R.P., Chorbov, V.M., Milanova, V.K., Kostov, C.S., Nickolov, K.I., Chakarova, C.F., Stoyanova, V.S., Nikolova-Hill, A.N., Krastev, S.K., Onchev, G.N., Kremensky, I.M., Kalaydjieva, L.V. and Jablensky, A.V. Linkage analysis in bipolar pedigrees adds support for a susceptibility locus on 21q22, Psychiatric Genetics, 14: pp 101-106 (2004)

King, C., Lacey, R., Rodger, J., Bartlett, C.A., Dunlop, S.A. and Beazley, L.D. Characterisation of tectal ephrin-A2 expression during optic nerve regeneration in goldfish: implications for restoration of topography, Experimental Neurology, 187: pp 380-387 (2004)

Kroeger, K.M., Pfleger, K. and Eidne, K.A. G-protein coupled receptor oligomerization in neuroendocrine pathways, Frontiers in Neuroendocrinology, 24: pp 254-278 (2004)

Kroeger, K.M. and Eidne, K.A. Study of GPCR-protein interactions by bioluminescence resonance energy transfer (BRET), Methods in Molecular Biology: Receptor Signal Transduction Protocols, 259: pp 323-334 (2004)

Laccone, F., Jünemann, I., Whatley, S., Morgan, R., Butler, R., Huppke, P. and Ravine, D. Large Deletions of the MECP2 Gene Detected by Gene Dosage Analysis in Patients With Rett Syndrome, Human Mutation, 23: pp 234-244 (2004)

Laing, N.G., Clarke, N.F., Dye, D.E., Liyanage, K., Walker, K.R., Kobayashi, Y., Shimakawa, S., Hagiwara, T., Ouvrier, R., Sparrow, J.C., Nishino, I., North, K.M. and Nonaka, I. Actin Mutations Are One Cause of Congenital Fibre Type Disproportion, Annals of Neurology, 56: pp 689-694 (2004)

Lalonde, J.P., Lim, R., Ingley, E., Tilbrook, P.A., Thompson, M.J., McCulloch, R., Beaumont, J.G., Wicking, C., Eyre, H.J., Sutherland, G.R., Howe, K., Solomon, E., Williams, J.H. and Klinken, S.P. HLS5, a Novel RBCC (Ring Finger, B Box, Coiled-coil) Family Member Isolated from a Hemopoietic Lineage Switch, Is a Candidate Tumor Suppressor, The Journal of Biological Chemistry, 279: pp 8181-8189 (2004)

Lee, C.M., Yeoh, G.C. and Olynyk, J.K. Differential effects of gadolinium chloride on Kupffer cells in vivo and in vitro, The International Journal of Biochemistry & Cell Biology, 36: pp 481-488 (2004)

Matthews, V.B., Rose-John, S. and Yeoh, G.C.T. Genetic Manipulations Utilizing Albumin and Alpha-fetoprotein Promoter/Enhancers Affect Both Hepatocytes and Oval Cells, Hepatology, 40:3, p 759 (2004)

Matthews, V.B., Klinken, E. and Yeoh, G.C.T. Direct effects of interleukin-6 on liver progenitor oval cells in culture, Wound Repair and Regeneration, 12: pp 650-656 (2004)

McCoubrie, J.E., Kendrick, T.S. and Minchin, R.F. HIV LTR-dependent expression of Bax selectively induces apoptosis in Tat-postive cells, Biochemical and Biophysical Research Communications, 325: pp 1459-1464 (2004)

Meredith, C., Herrmann, R., Parry, C., Liyanage, K., Dye, D.E., Durling, H.J., Duff, R.M., Beckman, S.K., de Visser, M., van der Graaf, M.M., Hedera, P., Fink, J.K., Petty, E.M., Lamont, P., Fabian, V., Bridges, L., Voit, T., Mastaglia, F.L. and Laing, N.G. Mutations in the Slow Skeletal Muscle Fiber Myosin Heavy Chain Gene (MYH7) Cause Laing Early-Onset Distal Myopathy (MPD1), American Journal of Human Genetics, 75: pp 703-708 (2004)

Miles, L.E.C., Hanyaloglu, A.C., Dromey, J.R., Pfleger, K.D.G. and Eidne, K.A. Gonadotropin-Releasing Hormone Receptor-Mediated Growth Suppression of Immortalized LβT2 Gonadotrope and Stable HEK293 Cell Lines, Endocrinology, 145: pp 194-204 (2004)

Morar, B., Gresham, D., Angelicheva, D., Tournev, I., Gooding, R., Guergueltcheva, V., Schmidt, C., Abicht, A., Lochmüller, H., Tordai, A., Kalmár, L., Nagy, M., Karcagi, V., Jeanpierre, M., Herczegfalvi, A., Beeson, D., Venkataraman, V., Carter, K.W., Reeve, J., de Pablo, R., Kučinskas, V. and Kalaydjieva, L. Mutation History of the Roma/Gypsies, American Journal of Human Genetics, 75: pp 596-609 (2004)

Morris, B.J., Adams, D.J., Beveridge, D.J., van der Weyden, L., Mangs, H. and Leedman, P.J. cAMP controls human renin mRNA stability via specific RNA-binding proteins, Acta Physiologica Scandinavica, 181: pp 369-373 (2004)

Müllner-Eidenböck, A., Moser, E., Klebermass, N., Amon, M., Walter, M.C., Lochmüller, H., Gooding, R. and Kalaydjieva, L. Ocular Features of the Congenital Cataracts Facial Dysmorphism Neuropathy Syndrome, Ophthalmology, 111: pp 1415-1423 (2004)

Nowak, K.J. and Davies, K.E. Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment, EMBO reports, 5: pp 872-876 (2004)

Oguma, T., Palmer, L.J., Birben, E., Sonna, L.A., Asano, K. and Lilly, C.M. Role of Postanoid DP Receptor Variants in Susceptibility to Asthma, New England Journal of Medicine, 351: pp 1752-1763 (2004)

Palmer, L.J., Valinsky, L., Pikora, T. and Landau, L.I. Do regular check ups and preventive drug use reduce asthma severity in school children?, Australian Family Physician, 33: pp 573-576 (2004)

Palmer, L.J., Buxbaum, S.G., Larkin, E.K., Patel, S.R., Elston, R.C., Tishler, P.V. and Redline, S. Whole Genome Scan for Obstructive Sleep Apnea and Obesity in African-American Families, American Journal of Respiratory and Critical Care Medicine, 169: pp 1314-1321 (2004)

Palmer, L.J. The New Epidemiology: putting the pieces together in complex disease aetiology, International Journal of Epidemiology, 33: pp 925-928 (2004)

Patel, S.R., Palmer, L.J., Larkin, E.K., Jenny, N.S., White, D.P. and Redline, S. Relationship between Obstructive Sleep Apnea and Diurnal Leptin Rhythms, Sleep, 27: pp 235-239 (2004)

Pfleger, K.D.G., Kroeger, K.M. and Eidne, K.A. Receptors for hypothalamic releasing hormones TRH and GnRH: oligomerization and interactions with intracellular proteins, Seminars in Cell & Developmental Biology, 15: pp 269-280 (2004)

Price, P., Santoso, L., Mastaglia, F.L., Garlepp, M., Kok, C.C., Allcock, R. and Laing, N.G. Two major histocompatibility complex haplotypes influence susceptibility to sporadic inclusion body myositis: critical evaluation of an association with HLA-DR3, Tissue Antigens, 64: pp 575-580 (2004)

Prinsen, B.H.C.M.T., Rabelink, T.J., Romijn, J.A., Bisschop, P.H., de Barse, M.M.J., de Boer, J., van Haeften, T.W., Barrett, P.H.R., Berger, R. and de Sain-van der Velden, M.G.M. A broad-based metabolic approach to study VLDL apoB100 metabolism in patients with ESRD and patients treated with peritoneal dialysis, Kidney International, 65: p 1064 (2004)

Rodger, J., Vitale, P.N., Tee, L.B.G., King, C.E., Bartlett, C.A., Fall, A., Brennan, C., O'Shea, J.E., Dunlop, S.A. and Beazley, L.D. EphA/ephrin-A interactions during optic nerve regeneration: restoration of topography and regulation of ephrin-A2 expression, Molecular and Cellular Neuroscience, 25: pp 56-68 (2004)

Saoudi, Y., Rousseau, B., Doussière, J., Charrasse, S., Gauthier-Rouvière, C., Morin, N., Sautet-Laugier, C., Denarier, E., Scaife, R., Mioskowski, C. and Job, D. Calcium-independent cytoskeleton disassembly induced by BAPTA, European Journal of Biochemistry, 271: pp 3255-3264 (2004)

Scaife, R.M. G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium, Molecular Cancer Therapeutics, 3: pp 1229-1237 (2004)

Schröder, J.M., Durling, H.J. and Laing, N.G. Actin myopathy with nemaline bodies, intranuclear rods, and a heterozygous mutation in ACTA1 (Asp154Asn), Acta Neuropathologica, 108: pp 250-256 (2004)

Schröder, M., Kroeger, K., Volk, H.D., Eidne, K.A. and Grütz, G. Preassociation of nonactivated STAT3 molecules demonstrated in living cells using bioluminescence resonance energy transfer: a new model of STAT activation?, Journal of Leukocyte Biology, 75: pp 792-797 (2004)

Silverman, E.S., Palmer, L.J., Subramaniam, V., Hallock, A., Mathew, S., Vallone, J., Faffe, D.S., Shikanai, T., Raby, B.A., Weiss, S.T. and Shore, S.A. Transforming Growth Factor-β1 Promoter Polymorphism C-509T Is Associated with Asthma, American Journal of Respiratory and Critical Care Medicine, 169: pp 214-219 (2004)

Simpson, B.J., Height, T.A., Rychkov, G.Y., Nowak, K.J., Laing, N.G., Hughes, B.P. and Bretag, A.H. Characterization of three myotonia-associated mutations of the CLCN1 chloride channel gene via heterologous expression, Human Mutation, 24: p 185 (2004)

Stoddart, C.W., Martin-Iverson, M.T., Jablensky, A. and Urosevic, N. A novel mouse Chr5 locus Diht controls dopamine-induced hypothermia, Mammalian Genome, 15: pp 901-913 (2004)

Tan, E., Besant, P.G., Zu, X.L., Turck, C.W., Bogoyevitch, M.A., Lim, S.G., Attwood, P.V. and Yeoh, G.C. Histone H4 histidine kinase display the expression pattern of a liver oncodevelopmental marker, Carcinogenesis, 25:9, pp 1-6 (2004)

Tannock, L.R., Little, P.J., Barrett, P.H.R., Tsoi, C., Wight, T.N. and Chait, A. Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans, Diabetologia, 47: pp 837-843 (2004)

Tantisira, K.G., Lake, S., Silverman, E.S., Palmer, L.J., Lazarus, R., Silverman, E.K., Liggett, S.B., Gelfand, E.W., Rosenwasser, L.J., Richter, B., Israel, E., Wechsler, M., Gabriel, S., Altshuler, D., Lander, E., Drazen, J. and Weiss, S.T. Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids, Human Molecular Genetics, 13: pp 1353-1359 (2004)

Turner, S.W., Khoo, S-K., Laing, I.A., Palmer, L.J., Gibson, N.A., Rye, P., Landau, L.I., Goldblatt, J. and Le souef, P.N. β2 adrenoceptor Arg16Gly polymorphism, airway responsiveness, lung function and asthma in infants and children, Clinical and Experimental Allergy, 34: pp 1043-1048 (2004)

Turner, S.W., Palmer, L.J., Rye, P.J., Gibson, N.A., Judge, P.K., Cox, M., Young, S., Goldblatt, J., Landau, L.I. and Le souef, P.N. The relationship between infant airway function, childhood airway responsiveness and asthma, American Journal of Respiratory and Critical Care Medicine, 169: pp 921-927 (2004)

Voon, D.C., Subrata, L.S., Karimi, M., Ulgiati, D. and Abraham, L.J. TNF and Phorbol Esters Induce Lymphotoxin-β Expression through Distinct Pathways Involving Ets and NF-κB Family Members, Journal of Immunology, 172: pp 4332-4341 (2004)

Wallgren-Pettersson, C., Pelin, K., Nowak, K.J., Muntoni, F., Romero, N.B., Goebel, H.H., North, K.N., Beggs, A.H. and Laing, N.G. Genotype-phenotype correlations in nemaline myopathy caused by mutations in the genes for nebuline and skeletal muscle α-actin, Neuromuscular Disorders, 14: pp 461-470 (2004)

Ward, B.K., Magno, A.L., Davis, E.A., Hanyaloglu, A.C., Stuckey, B.G.A., Burrows, M., Eidne, K.A., Charles, A.K. and Ratajczak, T. Functional Deletion of the Calcium-Sensing Receptor in a Case of Neonatal Severe Hyperparathyroidism, Journal of Clinical Endocrinology & Metabolism, 89: pp 3721-3730 (2004)

Welty, F.K., Lichtenstein, A.H., Barrett, P.H.R., Dolnikowski, G.G. and Schaefer, E.J. Interrelationships between human apolipoprotein A-I and apolipoproteins B-48 and B-100 kinetics using stable isotopes, Arteriosclerosis Thrombosis and Vascular Biology, 24: pp 1703-1707 (2004)

Winteringham, L.N., Kobelke, S., Williams, J.H., Ingley, E. and Klinken, S.P. Myeloid Leukemia Factor 1 inhibits erythropoietin-induced differentiation, cell cycle exit and p27Kip1 accumulation, Oncogene, 23: pp 5105-5109 (2004)

Yeap, B.B., Wilce, J.A. and Leedman, P.J. The androgen receptor mRNA, BioEssays: advances in molecular, cellular and developmental biology, 26: pp 672-682 (2004)

Yerkovich, S.T., Rigby, P.J., Fournier, P.A., Olynyk, J.K. and Yeoh, G.C.T. Kupffer cell cytokines interleukin-1β and interleukin-10 combine to inhibit phosphoenolpyruvate carboxykinase and gluconeogenesis in cultured hepatocytes, International Journal of Biochemistry & Cell Biology, 36:8, pp 1462-1472 (2004)

Zhivotovsky, L.A., Underhill, P.A., Cinnioğlu, C., Kayser, M., Morar, B., Kivisild, T., Scozzari, R., Cruciani, F., Destro-Bisol, G., Spedini, G., Chambers, G.K., Herrers, R.J., Yong, K.K., Gresham, D., Tournev, I., Feldman, M.W. and Kalaydjieva, L. The Effective Mutation Rate at Y Chromosome Short Tandem Repeats, with Application to Human Population-Divergence Time, American Journal of Human Genetics, 74: pp 50-61 (2004)

Conference Publications

Eidne, K.A., Dalrymple, M.B., Schmidt, U., Kroeger, K.M. and Pfleger, K. GPCR oligomerization - monitoring the formation of dynamic protein complexes in living cells, 12th International Congress of Endocrinology, Bologna, Spain, Medimont S.r.l, 1: pp 113-118 (2004)