Pharmacology

Books and Chapters

Goldie, R.G. and Henry, P.J. The involvement of endothelins in airway reactivity and disease, Endothelins and Its Inhibitors, ed Warner,T.D., United States, Springer Verlag, 152: pp 357-387 (2001)

Henry, P.J. and Goldie, R.G. Endothelin receptors, Endothelins and Its Inhibitors, ed Warner,T.D., United States, Springer Verlag, 152: pp 69-114 (2001)

Journal Articles

Begg, E.J., Malpas, T.J., Hackett, L.P. and Ilett, K.F. Distribution of R- and S-methadone into human milk during multiple, medium to high oral dosing, British Journal of Clinical Pharmacology, 52: pp 681-685 (2001)

Blythe, D. and Joyce, D.A. Clearance of arsenic by haemodialysis after acute poisoning with arsenic trioxide, Intensive Care Medicine, 27: p 334 (2001)

Bouzahzah, B., Albanese, C., Ahmed, F., Pixley, F., Lisanti, M.P., Segall, J.D., Condeelis, J., Joyce, D.A., Minden, A., Der, C.J., Chan, A., Symons, M. and Pestell, R.G. Rho Family GTPases Regulate Mammary Epithelium Cell Growth and Metastasis Through Distinguishable Pathways, Molecular Medicine, 7:12, pp 816-830 (2001)

Chan, C.F., Chiswell, G.M., Bencini, R., Hackett, L.P., Dusci, L.J. and Ilett, K.F. Quantification of naltrexone and 6,â-naltrexol in plasma and milk using gas chromatography-mass spectrometry. Application to studies in the lactating sheep, Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 761: pp 85-92 (2001)

Chan, V., Morris, R.G., Ilett, K.F. and Tett, S.E. Population Pharmacokinetics of Lamotrigine, Therapeutic Drug Monitoring, 23:6, pp 630-635 (2001)

Davis, T.M.E., Hoang, L.P., Ilett, K.F., Nguyen, C.H., Batty, K.T., Vu, D.B.P., Powell, S.M., Huynh, V.T. and Tran, Q.B. Pharmacokinetics and Pharmacodynamics of Intravenous Artesunate in Severe Falciparum Malaria, Antimicrobial Agents and Chemotherapy, 45:1, pp 181-186 (2001)

Goldie, R.G., Rigby, P.J., Fernandes, L.B. and Henry, P.J. The Impact of Inflammation on Bronchial Neuronal Networks, Pulmonary Pharmacology and Therapeutics, 14: pp 177-182 (2001)

Griese, E.U., Ilett, K.F., Kitteringham, N., Eichelbaum, M., Powell, H., Spargo, R.M., Le Souef, P.N., Musk, A.W. and Minchin, R.F. Allele and genotype frequencies of polymorphic cytochromes P4502D6, 2C19 and 2E1 in Aborigines from Western Australia, Pharmacogenetics, 11: pp 69-76 (2001)

Hale, T.W. and Ilett, K.F. Drug Therapy and Breastfeeding, Contemporary Clinical Gynecology and Obstetrics, 1:2, pp 129-148 (2001)

Hansen, T.G., Ilett, K.F., Reid, C., Lim, S.I., Hackett, L.P. and Bergesio, R. Caudal Ropivacaine in Infants: Population pharmacokinetics and plasma concentrations, Anesthesiology, 94: pp 579-584 (2001)

Hay, D.W.P., Douglas, S.A., Zhao, A., Ohlstein, E.A., Moesker, R.M., Self, G.J., Rigby, P.J., Luttman, M.A. and Goldie, R.G. Differential modulation of endothelin ligand-induced contraction in isolated trachea from endothelin B (ET?) receptor knockout mice, British Journal of Pharmacology, 132: pp 1905-1915 (2001)

Ilett, K.F., Kristensen, J.H., Hackett, L.P., Paech, M.J., Kohan, R. and Rampono, J. Distribution of venlafaxine and its O-desmethylmetabolite human milk and their effects in breastfed infants, British Journal of Clinical Pharmacology, 53: pp 17-22 (2001)

Ilett, K.F., Batty, K.T., Davis, T.M.E., Powell, S.M., Binh, T.Q., Hung, N.C., Thu, L.T.A., Phuong, H.L., Phuong, V.D.B. and Thien, H.V. Oral bioavailability of dihydroartemisinin in Vietnamese volunteers and in patients with falciparum malaria, British Journal of Clinical Pharmacology, 51: pp 541-546 (2001)

Joyce, D.A., Gimblett, G. and Steer, J.H. Targets of glucocorticoid action on TNF-? release by macrophages, Inflammation Research, 50: pp 337-340 (2001)

Kloda, A. and Martinac, B. Mechanosensitive Channel of Thermoplasma, the Cell Wall-Less Archaea, Cell Biochemistry and Biophysics, 34: pp 321-347 (2001)

Kloda, A. and Martinac, B. Molecular Identification of a Mechanosensitive Channel in Archaea, Biophysical Journal, 80: pp 229-240 (2001)

Kloda, A. and Martinac, B. Structural and functional differences between two homologous mechanosensitive channels of Methanococcus jannaschii, The EMBO Journal, 20:8, pp 1888-1896 (2001)

Kristensen, J.H., Hackett, L.P., Kohan, R., Paech, M. and Ilett, K.F. The amount of Fluvoxamine in Mils is Unlikely to be a Cause of Adverse Effects in Breastfed Infants, Journal of Human Lactation, 18:2, pp 139-143 (2001)

Kumar, P., Mark, P.J., Ward, B.K., Minchin, R.F. and Ratajczak, T. Estradiol-Regulated Expression of the Immunophilins Cyclophilin 40 and FKBP52 in MCF-7 Breast Cancer Cells , Biochemical and Biophysical Research Communications, 284: pp 219-225 (2001)

Kumar, P., Ward, B.K., Minchin, R.F. and Ratajczak, T. Regulation of the Hsp90-binding immunophilin, cyclophilin 40, is mediated by multiple sites for GA-binding protein (GABP), Cell Stress & Chaperones, 6:1, pp 78-91 (2001)

Lam, C.F. and van Heerden, P.V. Novel Nitric Oxide Donors as Selective Pulmonary Vasodilators - Review of the Pulmonary Circulation and the Potential Role of NONOates, Australasian Anaesthesia 2001, 2001: pp 45-62 (2001)

Lan, R.S., Knight, D.A., Stewart, G.A. and Henry, P.J. Role of PGE2 in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea, British Journal of Pharmacology, 130:1, pp 93-100 (2001)

Mark, P.J., Ward, B.J., Kumar, P., Lahooti, H., Minchin, R.F. and Ratajczak, T. Human cyclophilin 40 is a heat shock protein that exhibits altered intracellular localization following heat shock, Cell Stress & Chaperones, 6:1, pp 59-70 (2001)

Minchin, R.F., Carpenter, D. and Orr, R.J. Polyinosinic Acid and Polycationic Liposomes Attenuate the Hepatic Clearance of Circulating Plasmid DNA, The Journal of Pharmacology and Experimental Therapeutics, 296:3, pp 1006-1012 (2001)

Oakley, A.J., Ketterman, A. and Wilce, M.C.J. Structural Biology and Its Applications to the Health Sciences, Croatian Medical Journal, 42:4, pp 375-378 (2001)

Oakley, A.J., Jirajaroenrat, K., Harnnoi, T., Ketterman, A.J. and Wilce, M.C.J. Crystallization of two glutathione S-transferases from an unusual gene family, Acta Crystallographica Section D - Biological Crystallography, D57: pp 870-872 (2001)

Oakley, A.J., Harnnoi, T., Udomsinprasert, R., Jirajaroenrat, K., Ketterman, A.J. and Wilce, M.C.J. The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B, Protein Science, 10: pp 2176-2185 (2001)

Perozo, E., Kloda, A., Cortes, D.M. and Martinac, B. Site-directed Spin-labeling Analysis of Reconstituted Mscl in the Closed State, Journal of General Physiology, 118:August, pp 193-205 (2001)

Rangan, G.K., Wang, Y., Tay, Y-C. and Harris, D.C.H. Early Administration of PDTC in Adriamycin Nephropathy: Effect on Proteinuria, Cortical Tubulointerstitial Injury, and NF-?B Activation, Renal Failure, 23:6, pp 773-780 (2001)

Rangan, G.K., Wang, Y. and Harris, D.C.H. Induction of Proteinuric Chronic Glomerular Disease in the Rat (Rattus rattus) by Intracardiac Injection of Doxorubicin Hydrochloride, Contemporary Topics in Laboratory Animal Science, 40:5 / September, pp 44-49 (2001)

Rangan, G.K., Wang, Y. and Harris, D.C.H. Pharmacologic Modulators of Nitric Oxide Exacerbate Tubulointerstitial Inflammation in Proteinuric Rats, Journal of American Society of Nephrology, 12: pp 1696-1705 (2001)

Ratajczak, T. Protein coregulators that mediate estrogen receptor function, Reproduction, Fertility and Development, 13: pp 221-229 (2001)

Rodgers, A., Ewart, G., Cox, G. and Wilce, M. Crystallization and preliminary X-ray analysis of the complex of the å-subunit and the central domain of the ã-subunit from the Escherichia coli ATP synthase, Acta Crystallographica Section D - Biological Crystallography, D57: pp 722-724 (2001)

Rose, A.H., Ilett, K.F., O'Donoghue, H.L., Hackett, L.P., Penhale, W.J., Manning, L.S., Glancy, R.J., Cullen, L.K. and Turner, J.H. Cyclosporin immunosuppression of sheep: pharmacokinetics and allograft survival, Veterinary Immunology and Immunopathology, 81:1-2, pp 23-36 (2001)

Taylor, P., Dornan, J., Carrello, A., Minchin, R.F., Ratajczak, T. and Walkinshaw, M.D. Two Structures of Cyclophilin 40: Folding and Fidelity in the TPR Domains, Structure, 9:May, pp 431-438 (2001)

Tsunoda, S.P., Rodgers, A.J.W., Aggeler, R., Wilce, M.C.J., Capaldi, R.A. and Yoshida, M. Large conformational changes of the ? subunit in the bacterial F1F0 ATP synthase provide a ratchet action to regulate this rotary motor enzyme, Proceedings of the National Academy of Sciences of the United States of America, 98:12, pp 6560-6564 (2001)

van Heerden, P.V., Niazov, S., Webb, A., Carson, C., Hammer, K., Riley, T., Parsons, R. and Tinley, P. The effect of tea tree oil on pedal flora, Australasian Journal of Podiatric Medicine, 35:4, pp 103-106 (2001)

Vivian, J.P., Wilce, J.A., Hastings, A.F. and Wilce, M.C.J. Crystallization of the Bacillus subtilis RTP-DNA complex prepared using NMR spectroscopy, Acta Crystallographica Section D - Biological Crystallography, D57: pp 421-424 (2001)

Ward, B.K., Kumar, P., Turbett, G.R., Edmondston, J.E., Papadimitriou, J.M., Laing, N.G., Ingram, D.M., Minchin, R.F. and Ratajczak, T. Allelic loss of cyclophilin 40, an estrogen receptor-associated immunophilin, in breast carcinomas, Journal of Cancer Research and Clinical Oncology, 127: pp 109-115 (2001)

Wilce, J.A., Vivian, J.P., Hastings, A.F., Otting, G., Folmer, R.H.A., Duggin, I.G., Wilce, M.C.J. and Wake, I.G. Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest, Nature Structural Biology, 8:3, pp 206-210 (2001)

Yang, M., Hogan, S.P., Henry, P.J., Matthaei, K., McKenzie, A.N.J., Young, I.G., Rothenberg, M.E. and Foster, P.S. Requirement for IL-4R alpha and STAT-6, and not IL-5, eotaxin and eosinophils in early and late-phase IL-13 mediated AHR, American Journal of Respiratory Cell and Molecular Biology, 25: pp 522-530 (2001)

Zhang, S-Q., Hai, T.N., Ilett, K.F., Huong, D.X., Davis, T.M.E. and Ashton, M. Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers, British Journal of Clinical Pharmacology, 52: pp 377-385 (2001)

Conference Publications

Fernandes, L.B., D'Aprile, A.C. and Goldie, R.G. Respiratory syncytial virus infection in sheep bronchial explants is associated with enhanced ET? receptor-mediated contractile function, American Thoracic Society 2001 International Conference, United States, American Lung Association, 163: p A552 (2001)

Goldie, R.G. and D'Aprile, A.C. Parainfluenza-3 virus infection and endothelin (ET) receptor density and function in guinea-pig airways, American Thoracic Society 2001 International Conference, United States, American Lung Association, 163: p A146 (2001)

Others

Hammill, O.P. and Martinac, B. (Review)Molecular Basis of Mechanotransduction in Living Cells, 81:2, pp 685-740, United States (2001)

Joyce, D., Albanese, C., Steer, J.H., Fu, M., Bouzahzah, B. and Pestell, R.G. (Review)NF-?B and cell-cycle regulation: the cyclin connection, Cytokine and Growth Factor Reviews, 12: pp 73-90, United Kingdom (2001)

Kloda, A. and Martinac, B. (Review)Mechanosensitive Channels in Archaea, Cell Biochemistry and Biophysics, 34: pp 349-381, United States (2001)

Martinac, B. (Review)Mechanosensitive Channels in Prokaryotes, Cellular Physiology and Biochemistry, 11: pp 61-76, Germany (2001)

Schug, S.A. and Watson, D. Local Anaesthetics (2001), Side Effects of Drugs Annual 24, pp 140-156, Netherlands (2001)